Institute of Mathematics for Industry


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Biological Soliton in Multicellular Movement

Hold Date 2016-03-08 16:00~2016-03-08 17:00

Place Lecture Room M W1-C-512, West Zone 1, Ito campus, Kyushu University

Object person  

Speaker Hidekazu KUWAYAMA (University of Tsukuba)

Solitons have been observed in various physical phenomena mainly in physical fields. We showed that the distinct characteristics of solitons are present in the mass cell movement of non-chemotactic mutants of the cellular slime mould Dictyostelium discoideum (Kuwayama and Ishida, Scientific Reports, 3, Article number: 2272, 2013).

During starvation, D. discoideum forms multicellular structures that differentiate into spore or stalk cells and, eventually, a fruiting body. The non-chemotactic mutant cells do not form multicellular structures; however, they exhibited a characteristic structure with the features of a self-reinforcing solitary wave, or soliton. Under starvation conditions, the mutants do not aggregate but form an arc-shape multicellular structure, named the Soliton-Like-Structure (SLS). SLS movement continues much longer than the developmental cycle, moves at constant speed without changing shape, and does not obey the superposition principle. Even after collisions, waves pass through each other, conserving their physical qualities (Fig.1). They do undergo mass cell movement in the form of a pulsatile soliton-like structure (SLS). It was also found that SLS induction is mediated by adhesive cell-cell interactions. These observations provided novel insights into the mechanisms of biological solitons in multicellular movement.

In this seminar, the nature of the cellular slime mould and the feature of the biological soliton will be introduced.