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Models of solid tumor growth and therapy


Hold Date 2017-08-07 16:45~2017-08-07 17:45

Place Lecture Room M W1-C-515, West Zone 1, Ito campus, Kyushu University

Object person  

Speaker Benoit PERTHAME (Université Pierre et Marie Curie)

The special IMI Colloquium in August
 
Date : Monday,7 August 2017
          16:45-17:45
Place : Lecture Room M W1-C-515 (5F, West Zone 1, Kyushu University)
Speaker : Prof. Benoit PERTHAME (Université Pierre et Marie Curie,Full Professor)
 
Title : Models of solid tumor growth and therapy
 
Abstract :
The mechanical modeling of living tissues has attracted much attention in the last decade. Applications include tissue repair and growth models of solid tumors. In this latter case, these models are calibrated on medical images and help to predict the evolution of the disease, to decide of treatment scheduling and of the optimal therapy. They are also used to understand the biological effects that permit tumor growth. A more recent subject is to explain emergence of resistance to drugs and its implication in therapeutic failures.

These models contain several levels of complexity, both in terms of the biological and mechanical effects, and therefore in their mathematical description. The number of scales, from molecules to the organ and entire body, explains partly this complexity.

In this talk I shall give a general presentation of the field. departing from the simplest (and irrealistic) model of cell division moving by pressure forces, I will include several additional biological effects and explain the consequences in terms of qualitative behavior of solutions.
 


IMI Colloquium Report